BACKGROUND: Hepcidin is a 25-aminoacid cysteine-rich iron regulating peptide.Increased hepcidin concentrations lead to iron sequestration in macrophages, contributing to the pathogenesis of anaemia of chronic disease whereas decreased hepcidin is observed in iron deficiency and primary iron overload diseases such as hereditary hemochromatosis.Hepci
Positive clinical outcomes in adeno-associated virus (AAV)-mediated retinal gene therapy have often been attributed to the low immunogenicity of AAVs and immune privilege of the eye.However, several recent studies have shown potential for inflammatory responses.The current understanding of the factors contributing to inflammation, such as the pre-e
To analyze the risk factors influencing the crash injury severity in rural-urban fringes, crash data in rural-urban fringes were collected from Harbin, China.Four risk factors, namely, time of day, vehicle type, road feature, and crash type, were investigated associated with MAG Lamp the severity of rural-urban fringe crashes.The crash injury sever
Abstract The UNet architecture, based on convolutional neural networks (CNN), has demonstrated its remarkable performance in medical image analysis.However, it faces challenges in capturing long-range dependencies due to the limited receptive fields and inherent bias of convolutional operations.Recently, numerous transformer-based techniques have b
Many bark beetles of the subfamily Scolytinae are the most economically important insect pests of coniferous forests worldwide.In this study, we sequenced the mitochondrial genomes of eight bark beetle species, including Dendroctonus micans, Orthotomicus erosus, Polygraphus poligraphus, Dryocoetes hectographus, Ips nitidus, Ips typographus, Ips sub